General Information

  • ID:  hor003988
  • Uniprot ID:  NA
  • Protein name:  myotropin
  • Gene name:  NA
  • Organism:  Leptinotarsa decemlineata
  • Family:  Pyrokinin family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  GFKNVALSTARGF
  • Length:  13
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T13 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Stimulated the frequency, amplitude, and tonus of the myogenic oviduct contractions
  • Mechanism:  NA
  • Cross BBB:  NO
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor003988_AF2.pdbhor003988_ESM.pdb

Physical Information

Mass: 158179 Formula: C62H98N18O17
Absent amino acids: CDEHIMPQWY Common amino acids: AFG
pI: 11.65 Basic residues: 2
Polar residues: 5 Hydrophobic residues: 6
Hydrophobicity: 23.08 Boman Index: -1266
Half-Life: 30 hour Half-Life Yeast: >20 hour
Half-Life E.Coli: >10 hour Aliphatic Index 67.69
Instability Index: -886.15 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  8580496
  • Title:  Isolation and Characterization of Locusta Migratoria Accessory Gland Myotropin I (Lom-Ag-MT-I) From the Brain of the Colorado Potato Beetle, Leptinotarsa Decemlineata